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Case of the Week 623


What is the most likely diagnosis?

  • 38 year-old with blood dyscrasia



Frontal Chest Radiograph

  1. Multiple myeloma
  2. Idiopathic thrombocytopenia
  3. Thalassemia
  4. Pernicious anemia
  5. Neurofibromatosis

Additional Images - None

 

Additional Images

 

 

None


Answer:

3. Thalassemia

More (Click Discussion Tab)

 

 

Extramedullary hematopoiesis in Thalassemia

General Considerations

  • Response to insufficient blood cell production by production of blood elements outside of the marrow cavity
  • Most often due to hemolytic anemias such as sickle cell anemia, thalassemia and hereditary spherocytosis
  • May also be seen in prolonged iron deficiency anemia, myelofibrosis and sclerosis, polycythemia, leukemia and lymphoma

 

MORE . . .


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This Week

38 year-old with blood dyscrasia
 
 



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LearningRadiology.com
is an award-winning educational website aimed primarily at medical students and radiology residents-in-training, containing  lectures, handouts, images, Cases of the Week, archives of cases, quizzes, flashcards of differential diagnoses and “most commons” lists, primarily in the areas of chest, GI, GU cardiac, bone and neuroradiology.